Histology Course S XI 10 Department of Pathology, University of Zurich Histokurs

S XI 10 Granulosa cell tumor, adult type, ovary HE further information (German) on HiPaKu
  ICD-10: C56.9; ICD-O: 8620/1

62-year-old female, postmenopausal for15 years without bleeding, then multiple bleeding episodes and curettage with diagnosis of a sinple hyperplasia of endometrium located in the uterine body

- Solidly tumour tissue consisting of middle sized cells of the stroma type with poorly defined cell borders
- The nuclei appear round, oval or square and are mostly light in colour, often with indentation. Occasional mitoses can be seen.
- The tumour produces oestrogen, causing recurrent postmenopausal bleeding and presents as  a simple hyperplasia of  uterine body endometrium.