Histology Course S X 7 Department of Pathology, University of Zurich Histology Course

S X 7 papillary thyroid carcinoma, lymph node metastastis  HE further information (German) on HiPaKu
  ICD-10: C73.9, C77.0; ICD-O: 8260/3, 8260/6
 
 


38 year old female, enlarged painless lymph node on the right side of the neck. Excision of lymph node.

- Partly cystic tumour with formation of papillae surrounded by a capsule of varying thickness
- Partly papillary structures covered by cuboidal cells, partly cylindrical cells, fibrovascular stroma
- Tumour infiltration of the capsule
- The tumour tissue contains some individual islands of lymphatic tissue: remnant of lymph node
- Some tumour cells have nuclei with a milk glass appearance
- Central clearing of nuclei
- Some of the nuclei overlap
- Nuclear grooves and inclusions


The papillary thyroid carcinoma typically spreads along the lymphatic vessels. The prognosis is good: 15-year survival is 80-90%.