Histology Course S X 5 Department of Pathology, University of Zurich Histology Course

S X 5 hyperthyroidism (Graves' disease)   IHC: Ig further information (German) on HiPaKu
  ICD-10: E05.0

48-year-old female, thyroidectomy after unsuccessful drug treatment of hyperthyroidism with anti-thyroid drugs

- Small to medium sized, irregularly formed thyroid follicle with little or no colloid
- The epithelium is epithelium and contains several layers in parts with papillary epithelial proliferation(hyperplasia).

immunological hypersensitivity reaction type II; antibodies (TSI= thyroid stimulating immunoglobins) stimulate the TSH receptor and mimic the effect of TSH.

symptoms of increased T3 and T4 secretion. Hyperthyroidism increased synthesis of structural proteins of thyroid gland lead to hyperplasia and the development of a goitre