Histology Course S VIII 12 Departement of Pathology, University of Zurich Histokurs

S VIII 12 tuberculosis, kidney HE  
  ICD-10: A18.1+ N29.1*

45-year-old male, experienced tuberculous pleuritis at the age of 20. An investigation of microhaematuria led to this incidental finding. Nephrectomy specimen.

- Inflamed foci with partly granulomatous inflammation throughout the kidney.
- The centre contains some changed and degenerating tubuli, corresponding to canalicular propagation of infection.
- Next to this is a large cavernous area, which is characteristically lined by an epithelioid granuloma and contains giant cells.
- The remaining renal tissue shows atrophy and an intersitital fibrosis, especially in the periglomerular areas