Histology Course S VII 2 Department of Pathology, University of Zurich Histology Course

S VII 2 acute cerebral infarction (stage I), cerebrum HE  
  ICD-10: I63.9

35-year-old patient,  Past mitral valve replacement following endocarditis caused by rheumatic fever. Embolism.

- Distinct demarcation of recently infarcted CNS tissue, perifocal oedema
- The necrotic tissue shows a pattern of previously structured  CNS tissue
- Individual macrophages invade and accumulate in the bordering edges.