Histology Course S VII 19 Department of Pathology, University of Zurich Histology Course

S VII 19 glioblastoma multiforme HE further information (German) on HiPaKu
  ICD-10: C71.9; ICD-O: 9440/3

65-year-old male. Healthy until 3 weeks ago. Then headache, personality change, sporadic convulsions. The CT scan shows large tumour in left fronto-temporal area.  Autopsy revealed a large diffuse infiltrating tumour in the left frontotemporal lobe with multicoloured cut surface. Yellow sections (necrosis) with solid, grey-whitish tumour tissue as well as several haemorrhagic foci.

- The tumor is polymorphous, in some parts relatively rich in cells.
- Areas and lines of tumour tissue necrosis.
- Extensive vessel proliferation
- Diffuse tumour infiltration of CNS tissue
WHO grade IV