Histology Course S V 9 Department of Pathology, University of Zurich Histology Course

S V 9 non-Hodgkin's lymphomas, large cell   Giemsa further information (German) on HiPaKu
  ICD-10: C83.3; ICD-O: 9591/3

20-year-old female with sudden-onset, painless swelling of a cervical lymph node. No constitutional symptoms. Good general health.

- Enlarged lymph node with blastic cell populations
- Some cells show a basophilic cytoplasm and large vesicular nuclei with large, central nucleoli (immunoblasts) or a double nucleolus at the cell membrane (centroblasts).
- Plenty of mitoses can be seen.

Highly malignant NHL, which takes an aggressive course if left untreated. Often curable thanks to modern chemotherapy.