Histology Course S V 8 Department of Pathology, University of Zurich Histology Course

S V 8 non-Hodgkin's lymphomas, diffuse, small cell HE  
  ICD-10: C83.0; ICD-O: 9591/3

70-year-old male with painless enlargement of several lymph nodes in various places and anaemia Lymph node biopsy.

- Lymph node diffusely overgrown with small lymphocytes
- The lightly shaded zones are areas of increased proliferation, called pseudonodules.

Lymphoma of lowgrade malignancy. Often initially stage IV (blood, bone marrow). The lymph node has the appearance of CLL.