Histology Course S V 11 Department of Pathology, University of Zurich Histology Course

S V 11 acute myelogenous leukemia (AML), bone marrow     Chlorazetatesterase (CHL) further information (German) on HiPaKu
  ICD-10: C92.0; ICD-O: 9861/3

55-year-old male with generalised weakness, anaemia, bleeding tendency, in peripheral blood
100 000 white cells, 80% of which myeloblasts.

- Bone marrow, massively hypercellular given the patient’s age.
- extensive infiltration by blast cells negative for chloracetatesterase, replacing comepletely the normal hematopoiesis.
- Zytogenetics showed a translocation t(2;5) indicating an intermediate risk for this acute myeloid leukemia.