Histology Course S IX 7 Department of Pathology, University of Zurich Histology Course

S IX 7 synovitis due to chronic polyarthritis HE further information (German) on HiPaKu
  ICD-10: M65.9

52-year-old female, chronic pain of finger, hand and shoulder joint. Now pain and swelling of knee. Arthroscopy and biopsy.

- Plump, villous tela synvovialis, covered by multiple layers of covering cells(possibly fibrin)
- The stroma contains lymphocytic and plasma cell infiltrates with development of lymphoid follicles.
- Occasional lesions of the covering cell layer can be due to granulocytic infiltrates.

Comment: A pathological finding is suggestive for chronic polyarthritis  but not pathognomonic. History, clinical findings and serology are essential.