45-year-old male, hoarse voice, irritable cough, laryngoscopy shows
nodules on vocal cords. Excision.
Macroscopically: a lucent grey round "tumour" localised
especially at the junction between first and second third of the
vocal cord, occasionally bilateral.
- One or more polypoid mucosal fragments covered by squamous epithelium
- Oedematous or myxomatous stroma, fibrinoid swelling, fresh bleeding
and bleeding residues (siderophages)
- Fibrotic areas
- Numerous vessels partly dilated forming thin-walled cavities;
in later stages increased thickening of the wall
- Inflammatory infiltrates
Pathogenesis: excessive mechanical straining of vocal cords.
Mechanische Überbelastung der Stimmlippen.