Histology Course S IV 19 Department of Pathology, University of Zurich Histokurs

S IV 19 small cell lung cancer HE further information (German) on HiPaKu
  ICD-10: 34.9; ICD-O: 8041/3

55-year-old male. Smoker, general deterioration of health, autopsy specimen.

- Lung tissue with bronchi (recognisable by cartilage)
- Bronchi and lung tissue partially destroyed by invasively growing tumour
- Relatively small tumour cells (cells slightly larger than small lymphocytes) of round or oval shape. Thin, hardly visible rim of cytoplasm (“naked nuclei”)
- Numerous individual necrotic cells (pyknosis)
- Areas of necrotic tumour
- Little stroma with only minimal inflammatory infiltration
- Marked lymphangitis carcinomatosa in the surroundings