61-year-old male, 25 worked in the asbestos industry for 25 years.
Increasing striated reticular, mainly basal shadowing on chest X-ray.
Progressive dyspnoea. Autopsy specimen.
- Partly destroyed lung architecture
- Varying degree of fibrosis. Less affected sections show fibrosis
especially in the lobal periphery.
- Ferruginous bodies (in the given specimen these are real asbestos
particles): dumbbell-like segmented bodies with coat containing
iron and/or protein and central asbestos fibres.
- Pigment deposits: anthracosis and formalin pigment, little haemosiderin
Differential diagnosis: any other cause of fibrosis. The evidence
of numerous Ferruginous bodies points towards asbestosis. In contrast
to specimen S IV 12 this is an example of fibrosis of known aetiology.