Histology Course S IV 10 Department of Pathology, University of Zurich Histokurs

S IV 10 ARDS (adult) HE  
  ICD-10: J80

30-year-old male, accident with resulting hypovolaemic shock. Death after 3 days due to respiratory failure. Autopsy specimen.

- Lung tissue with dilated capillaries and interstitial oedema
- Microthrombi ( hardly seen in the given specimen)
- Alveolar septa not covered by epithelium
- Clusters of hyaline membranes
- cClusters of increased numbers of type II pneumocytes: cuboid metaplasia, i.e. the alveolar walls are lined by large cuboid cells. The cells are partially detached and arranged as a chain in the alveoli.
- Macrophages in the alveolar lumen
- Some alveoli have collapsed so that the alveolar walls touch.