Histology Course S IV 1 Department of Pathology, University of Zurich Histokurs

S IV 1 chronic allergic rhinitis/sinusitis HE further information (German) on HiPaKu
  ICD-10: J31/J32

40-year-old male with blocked nose and increased mucous production. Surgical excision of nasal polyps.

Macroscopically round, lucent grey, shiny polypoid excision biopsy specimen.

- One or more mucosal fragments, markedly oedematous stroma, forming polypoid structures.
- Ciliated epithelium of the surface, in some sections replaced by metaplastic squamous epithelium.
- Lymphocytic and plasma cell infiltrates and often numerous granulocytes in the oedematous stroma
- Hyperplasia of Goblet cells
- Clusters of mucosal glands, partly with cystic dilation
- Thickened basal membrane