Histology Course S III 9 Departement of Pathology, University of Zurich Histokurs

S III 9 coronary artery, hard plaque Orcein-Sirius  
  ICD-10: I25.1

75-year-old male. Triple vessel disease. Collapse and death at bus stop.

Macroscopically: proximal high-grade stenosis of all three coronary arteries

- In contrast to specimen SIII8, the intima plaques consist of hyalinised collagen fibres (hard plaques do not rupture)
- Another possibility: the atheroma foci ( like specimen SIII8) could be deposited in the media, covered by a thick layer of collagen fibres; in which case the risk of rupture would also be low.- Low-grade atrophied skip lesions in the media