Histology Course S III 10 Departement of Pathology, University of Zurich Histokurs

S III 10 coronary artery, rupture of the plaque Orcein-Sirius further information (German) on HiPaKu
  ICD-10: I25.1

48-year-old male, death due to cardiac tamponade due to large anterolateral myocardial infarction with rupture, occlusion of the proximal segment of the circumflex artery
Autopsy specimen

- The overview is difficult to assess since blood dominates and invades broken intima
- The intima is irregularly expanded by an amorphous mass with cholesterol crystals.
- On one side: in the atheroma, blood mixed with foam cells and cholesterol needles
- On the opposite side: content of atheroma (cholesterol and foam cells) within the thrombus
- In contrast to specimens SIII8 and 9, the atrophy in some parts of the media is so advanced that the intima and adventitia are almost adjacent.