70-year-old male with haemorrhagic shock (bleeding duodenal/stress
ulcer) after myocardial infarction. Autopsy preparation.
- Massive necrosis of parenchyma (coagulation necrosis with vaguely
visible trabecular structure. In contrast, colliquation necrosis
leaves an empty mesh.) Usually, a ring of periportal parenchyma
remains. (zone 1 of the acinus according to Rappaport).
- In the remaining parenchyma focal steatosis (mainly large drops)
- Loose infiltration with multisegmented leucocytes
- An invasion of macrophages has not yet occurred (recent lesion
in contrast to specimen SII 4)
The distribution pattern also occurs in necrosis of the liver due
to other causes such as intoxication (e.g Amanita phalloides) or
medication in toxic doses (acetaminophen).