70-year-old male with rapid weight loss, epigastric pain, nausea&vomiting,
mild icterus. Ultrasound shows a tumour in the area of the pancreatic
- Large tumour masses consisting of solid cell groups and tubular
- Abundant stroma in which the tumour grows as individual tubules
- Within the tubules and in the tumour cells: PAS-positive material
- Necrosis of the tumour tissue
- The endocrine islands remain intact. The practically inexistent
exocrine pancreatic tissue is replaced by fibrosis resulting in
obstructive chronic pancreatitis.
The obstructive pancreatitis often occurs as a consequence of the
disturbed flow in the pancreatic duct or one of the neighbouring
ductules in the head of the pancreas.