Histology Course S I 25 Department of Pathology, University of Zurich Histokurs

S I 25 adenoid cystic carcinoma HE further information (German) on HiPaKu
  ICD-10: C08.9; ICD-O: 8200/3


58-year-old female with painful swelling in the base of the tongue.

- Tumour diffusely extending to the striated muscle tissue and to the resection margin
- Characteristic cribriform, partially tubular architecture
- Pseudocystic spaces filled with alcian blue positive (not shown here) mucoid or hyaline eosinophilic material
- These spaces are surrounded by small monomorphous, elongated cells with dense chromatin
- Typical infiltration of the perineural border (PNI)