Histology Course S I 23 Department of Pathology, University of Zurich Histokurs

S I 23 autoimmune sialadenitis (Sjögren's syndrome)  IHC: LU-5 further information (German) on HiPaKu
  ICD-10: M35.0+ K11.2*

55-year.old female, rheumatoid arthritis, keratoconjunctivitis sicca, xerostomia and painless bilateral swelling of the parotid gland. Excision of the parotids.

- Extensive lymphocytic infiltration of the gland
- Extensive destruction of the parenchyma with essentially full loss of gland acini
- Proliferation of the canaliculi with development of epithelial islands (proliferating canaliculi as well as little remaining parenchyma. LU5 positive)