Histology Course S I 16 Department of Pathology, University of Zurich Histokurs

S I 16 adenocarcinoma Dukes B, colon HE further information (German) on HiPaKu
  ICD-10: C18.9; ICD-O: 8140/3

63-year-old male. Alternating constipation and diarrhoea with bloody stools. Endoscopy shows an ulcer in the sigmoid colon with wide raised margins.
- Cross section through the colon. A tubular, well to moderately differentiated adenocarcinoma which ulcerates the mucosa and extends into the muscularis propria makes up approximately half of the circumference. There is no penetration of the muscle layer.

If no lymph node metastases are found the classification would be a Duke Stage B 1 (according to the modified classification of Astler and Coller, 1954)