Histology Course S I 11 Department of Pathology, University of Zurich Histokurs

S I 11 diverticulitis of the sigmoid HE further information (German) on HiPaKu
  ICD-10: K57.3

75-year-old female. Intermittent diffuse lower abdominal pain with cramps, constipation, infrequent diarrhoea, occasional blood in stools.$

- The mucosa and submucosa of the sigmoid colon are thrown into large folds (probably due to the increased muscular tension) but their structures are still clearly visible.
- At several points the mucosa the mucosa dips into the hypertrophic muscularis propria and forms diverticula, some of which extend into the subserosal fat (FG).
-These diverticula are often surrounded by an inflammatory, sometimes also follicular infiltrate, and can occasionally (visible only on some specimens) become necrotic, which leads to the formation of abscesses. A foreign body reaction with giant cells (RZR)?? occurs in the presence of faecal components.
- The chronicity of the disease is evident from the extending scar tissue in the subserosa.