75-year-old female. Intermittent diffuse lower abdominal pain with
cramps, constipation, infrequent diarrhoea, occasional blood in
- The mucosa and submucosa of the sigmoid colon are thrown into
large folds (probably due to the increased muscular tension) but
their structures are still clearly visible.
- At several points the mucosa the mucosa dips into the hypertrophic
muscularis propria and forms diverticula, some of which extend into
the subserosal fat (FG).
-These diverticula are often surrounded by an inflammatory, sometimes
also follicular infiltrate, and can occasionally (visible only on
some specimens) become necrotic, which leads to the formation of
abscesses. A foreign body reaction with giant cells (RZR)?? occurs
in the presence of faecal components.
- The chronicity of the disease is evident from the extending scar
tissue in the subserosa.