42-year female was diagnosed with AML 1 year before death (specimen from autopsy).
- Hypercellular bone marrow in which fat and normal hematopoiesis are nearly completely replaced by immature appearing leukemic cells (packed marrow). Only scant residual erythropoiesis is observed.
- Majority of the cells are large blasts with quite abundant cytoplasm. Apoptoses are conspicuous.
Possible complication: opportunistic pneumonia with fungi (see slideA