Histology Course A IV 5 Department of Pathology, University of Zurich Histokurs

A IV 5 chronic unspecific tonsillitis HE further information (German) on HiPaKu 
  ICD-10: J35.0
 
   
8-year-old boy suffered from recurrent acute tonsillitis. Resection of the nasopharyngeal tonsil (adenoids).
 
- Pronounced enlargement of adenoids.
- Follicular hyperplasia marked by large germinal centers displaying numerous mitotic figures, centrocytes, centroblasts, macrophages containing nuclear debris (tingible body macrophages) and dendritic cells.
- Interfollicular hyperplasia consisting mainly of T-cells and postcapillary venules containing circulating lymphocytes.
- Plasma cells are localized around the follicles, below and within the epithelium.
- Crypts may display retention of cellular debris, bacteria, fungi and remnants of food (antigenic stimulation).

 
Complication of acute tonsillitis may be formation of a peritonsillar abscess.