45-year-old female experienced sharp pain in the right upper quadrant. Biliary colic due to gallstones was suspected and cholecystectomy was performed.
- Wall of the gall-bladder is substantially thickened (normal diameter 1 - 2 mm).
- Substantial fibrosis of the entire wall.
- Hypertrophy and fibrosis of muscularis propria. The latter is split apart by strands of fibrous tissue.
- Subserous fatty tissue is permeated by fibrous tissue containing numerous capillaries.
- Mucosal epithelium partly denuded.
- Wall infiltrated by lymphocytes, macrophages and interspersed eosinophilic granulocytes.