Male, 66 y., had a history of angina pectoris. He experienced prolonged chest pain radiating down the arm, cardiogenic shock ensued (specimen from autopsy).
- A transmural section of the left ventricle is shown.
- A vast, irregular area is observed with extensive coagulative necrosis of cardiomyocytes. The latter exhibit a homogenous hypereosinophilic cytoplasm and loss of nuclei. The necrosis is partly demarcated by an infiltrate of neutrophils.
- The visceral pericardium is infiltrated by inflammatory cells and covered by a layer of fibrin.
- A small subendocardial layer of viable cardiomyocytes is preserved, some displaying vacuolar degeneration.
atherosclerotic coronary artery obstruction with formation of an occlusive thrombus