Histology Course A III 7 Department of Pathology, University of Zurich Histology Course

A III 7 antral mucosa with complete intestinal metaplasia in type B gastritis HE further information (German) on HiPaKu 
  ICD-10: D37.1
 
   
72-year-old female underwent partial gastrectomy because of gastric cancer.
 
A tissue section of the mucosa distant from the tumor is shown:
- Antral gastric mucosa with regular architecture.
- Some of the glands exhibit a high number of intestinal goblet cells and Paneth cells, the latter with a strongly eosinophilic granulated cytoplasm (complete intestinal metaplasia).
- Moderate chronic, minimally active inflammation with formation of numerous lymphoid aggregates.
 
Care has to be taken not to confuse gastric mucosa exhibiting intestinal metaplasia with enteric or colonic mucosa.