68-year-old male underwent suprapubic prostatectomy because of urinary retention and dysuria.
- Increased number of partly dilated glands that are lined by pale epithelial cells. Papillary infoldings are frequent (hyperplasia of the glandular compartment).
- Stromal proliferation with hyperplasia of smooth muscle cells and connective tissue, leading in part to formation of nodules.
- Focal inflammatory infiltrates.
Hyperplasia originates in the inner part of the gland (portions around urethra), sparing the outer gland (which is also known as the surgical capsule).
Complications: Obstruction of urethra, dysuria, urinary retention.
Differential diagnosis: Carcinoma of the prostate (A IV 49)
Macroscopy: Enlarged prostate with an elastic to firm consistency. Formation of nodules.