Histology Course A III 36 Department of Pathology, University of Zurich Histology Course

A III 36 venous thrombosis in organization  IHC: Vi further information (German) on HiPaKu 
  ICD-10: I82
 
   
76-year-old female patient was immobilized due to advanced chronic polyarthritis (specimen from autopsy).
 
- A large vein is shown the lumen of which is occluded by a red thrombus or stasis thrombus.
- At one edge, ingrowths of granulation tissue are observed (organization of the thrombus).
- Staining for vimentin was performed. Vimentin is an intermediate filament present in virtually all normal mesencymal cells. Thus, endothelial cells, fibroblasts and smooth muscle cells stain intensely positive in the organized part of the thrombus.