72-year-old female succumbed to metastasized carcinoma of the breast (specimen from autopsy).
- Large portions of the myocardium are replaced by partly dense fibrous tissue (Sirius-red) consisting of wavy bundles of dense collagen (type I collagen) with presence of only few fibroblasts / fibrocytes (old scar tissue). In some sections of the scar tissue the collagen is less dense and wide capillaries can still be observed.
- The scar tissue is irregularly outlined, entrapping in some parts surviving cardiomyocytes.
- Subendocardial cardiomyocytes are also viable.